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It’s the result of interacting biological systems—energy metabolism, oxidative stress, immune signaling, and structural integrity—changing over time

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In another study involving mouse cardiomyocytes, co-exposure to PS-NPs and cadmium (Cd) led to both pyroptosis and necroptosis, a phenomenon referred to as PANoptosis, highlighting a complex interplay of multiple cell death pathways in response to nanoparticle exposure [80]